Healthcare
In the Nasdaq-100.
Your signal
Hold: 45 is between your Sell line (40) and Buy line (60). Off the high (−13% from its 1-year high) scores 57 and lifts it; Plays in (33%) scores 33 and holds it back.
Every factor in this score has a tested record: each was checked month by month since 2011 on numbers public at the time.
| Factor you weight | VRTX | Points | Weight | Adds |
|---|---|---|---|---|
| Plays in | 33% | 33 | 40 | 13.2 |
| Off the high | −13% from its 1-year high | 57 | 30 | 17.1 |
| Trend | +2% vs 200-day | 50 | 30 | 15.0 |
Your signal is the one call Be The Puck makes on a stock, and you set it: weight the plays, analysts, P/E, growth, debt, trend and more, and move the Buy and Sell lines. Every page follows your choice. How the score works
| Factor | VRTX | Points | What it is |
|---|---|---|---|
| Plays in | 33% | 33 | The share of the plays you count that hold it now. |
| Analysts' upside | +18% · 28 analysts | 54 | How far analysts' average 12-month target sits above the price (3+ analysts). −20% scores 0, +50% full marks; at most 50 while the price is below its 200-day average, since targets lag a falling price. |
| Analysts' rating | 1.6 · buy | 69 | The analysts' average recommendation: strong buy scores 100, hold or worse 0. |
| P/E | 28.3× | 44 | Price over the last four quarters' earnings per share. Lower ranks higher; a loss scores 0. Source: SEC filings to 2026-06-30. |
| Forward P/E | 24.0× | 21 | Price over next year's expected earnings. Lower ranks higher; an expected loss scores 0. Source: Yahoo Finance. |
| PEG | 1.90 | 34 | P/E divided by expected earnings growth. Lower ranks higher; around 1 is often read as fair for the growth. Source: Yahoo Finance. |
| Price to sales | 9.8× | 16 | Market value over the last 12 months' revenue. Lower ranks higher. Source: SEC filings to 2026-06-30. |
| Price to book | 6.1× | 28 | Price over book value (assets minus debts) per share. Lower ranks higher. Source: SEC filings to 2026-06-30. |
| Dividend yield | none | 0 | Dividends over the last year as a share of the price. Higher ranks higher; no dividend scores 0. Source: Yahoo Finance. |
| Earnings growth | +22% | 51 | Earnings per share over the last four quarters against the four before (the latest quarter on a year earlier where filings aren't available). Higher ranks higher. Source: SEC filings to 2026-06-30. |
| Revenue growth | +10% | 40 | Revenue over the last four quarters against the four before (the latest quarter on a year earlier where filings aren't available). Higher ranks higher. Source: SEC filings to 2026-06-30. |
| Profit margin | 35% | 89 | Net profit as a share of revenue. Higher ranks higher. Source: SEC filings to 2026-06-30. |
| Return on equity | 22% | 72 | Profit as a share of shareholders' equity. Higher ranks higher. Source: SEC filings to 2026-06-30. |
| Debt to equity | 0.01× | 95 | Debt against shareholders' equity. Lower ranks higher; negative equity scores 0. Source: SEC filings to 2026-06-30. |
| Off the high | −13% from its 1-year high | 57 | How far the price sits below its highest close of the last year: 100 points at the high, none at 30% or more below. The exit rule: a stock that keeps falling loses points whatever else it has going for it. |
| Trend | +2% vs 200-day | 50 | How far the price sits above its 200-day average. Higher ranks higher. |
| 1-year momentum | +19% | 56 | The price change over the last 12 months. Higher ranks higher. |
| Low crash exposure | 0/10 · low | 100 | The storm test: 100 for no exposure, 10 points off per point of exposure. |
The read
Test a theory on VRTXThis analysis does not constitute trading advice. Please meet with an advisor or independently review sources before making any decision. New to this? Start with the basics.
Each family's play whose calls went the right way most often, tested on 351 stocks since 2005, and what it says about VRTX now.
A call is right when the stock rose after an in call or fell after an out call. Trend plays are built to take many small losses for a few big wins, so their hit rates run lower; being right often isn't the same as making the most money. How we test a play.
Each candle is one trading day: the box spans the open and close, the thin line the day's high and low. Hollow boxes closed up, filled boxes closed down. Toggle the averages to see the trend the plays read. Dots above the candles mark news and company filings: hover or tap one to see the story and how the stock moved from the last close before it, against the market on the same days.
Its biggest move against the S&P 500 in the last 30 sessions, the news read on each, and how reliably that kind of news has moved stocks before. How it's measured
VRTX −4.3%, the S&P 500 0.0% that session.
Vertex Pharmaceuticals Inc Stock (VRTX) Moved Down by 3.13% on Oct 13: What Investors Need To Know
Citi Sticks to Its Buy Rating for Vertex Pharmaceuticals (VRTX)
One row per play, grouped by family. When most rows turn green at once, the trend is broad. When they split, the plays disagree and the stock is usually chopping sideways.
All 100 plays, by family.
Calls right: how often the play's calls on VRTX went the right way since 2005. Record columns: play / buy and hold, annual return and worst drawdown since 2005. Click a column to sort.Sort with the menu above the list.
| Play | Call | Since | Next move | Calls right | Annual return | Worst drawdown |
|---|---|---|---|---|---|---|
| Trend following | ||||||
| PB EMABitcoin Playboy · daily | OUT | Oct 1, 2026 −4.2% | Enter above $511.11 (+5.3%) | 23% 160/684 | −3.3% / +19.4% | −90.0% / −67.7% |
| Bull Market Support BandBenjamin Cowen · weekly | IN | Jun 18, 2026 +7.4% | Exit below $498.09 (+2.7%) | 25% 31/122 | +1.4% / +19.4% | −78.8% / −67.7% |
| Ripster EMA CloudRipster · daily | OUT | Oct 1, 2026 −4.2% | Enter above $513.30 (+5.8%) | 18% 76/412 | +2.3% / +19.4% | −76.2% / −67.7% |
| Trend TemplateMark Minervini · daily | OUT | Oct 1, 2026 −4.2% | Enter above $530.27 (+9.3%) | 13% 30/226 | −3.5% / +19.4% | −85.5% / −67.7% |
| Stage AnalysisStan Weinstein · weekly | IN | Jun 26, 2026 −1.2% | Exit below $477.35 (−1.6%) | 18% 18/98 | +0.2% / +19.4% | −74.9% / −67.7% |
| Stage 2 + Mansfield RSStan Weinstein · weekly | OUT | Oct 2, 2026 −3.9% | Enter above $512.17 (+5.6%) | 24% 27/113 | +1.9% / +19.4% | −73.6% / −67.7% |
| 10-Month SMAMeb Faber · month-end | IN | May 29, 2026 +8.4% | Exit below $481.04 (−0.9%) | 22% 11/50 | +3.7% / +19.4% | −65.0% / −67.7% |
| 200-Day RulePaul Tudor Jones · daily | IN | Jun 11, 2026 +9.0% | Exit below $475.31 (−2.0%) | 11% 22/202 | +1.2% / +19.4% | −81.1% / −67.7% |
| Golden CrossMarket tradition · daily | IN | Jun 29, 2026 −2.9% | Not on one close | 21% 9/42 | +1.6% / +19.4% | −82.4% / −67.7% |
| Granville 200-DayJoseph E. Granville · daily | IN | Jun 11, 2026 +9.0% | Exit below $475.31 (−2.0%) | 11% 14/128 | +1.1% / +19.4% | −79.9% / −67.7% |
| Hull Moving AverageAlan Hull · weekly | OUT | Oct 2, 2026 −3.9% | Enter above $559.65 (+15.3%) | 38% 54/143 | +8.5% / +19.4% | −46.6% / −67.7% |
| Kaufman Adaptive MAPerry J. Kaufman · daily | OUT | Oct 1, 2026 −4.2% | Enter above $506.85 (+4.5%) | 22% 189/842 | −6.7% / +19.4% | −92.8% / −67.7% |
| TEMA CrossoverPatrick G. Mulloy · daily | OUT | Sep 8, 2026 −8.3% | Enter above $605.63 (+24.8%) | 33% 87/266 | −0.8% / +19.4% | −71.2% / −67.7% |
| Seykota 15/150Ed Seykota · daily | IN | Jun 22, 2026 +3.9% | Not on one close | 21% 9/42 | +0.7% / +19.6% | −86.1% / −67.7% |
| Guppy Multiple MAsDaryl Guppy · daily | OUT | Oct 2, 2026 −3.9% | Enter above $583.37 (+20.2%) | 23% 35/153 | +1.7% / +19.4% | −63.8% / −67.7% |
| Ichimoku CloudGoichi Hosoda · daily | OUT | Oct 12, 2026 −4.3% | Not on one close | 26% 36/141 | +2.7% / +19.4% | −67.9% / −67.7% |
| SupertrendOlivier Seban · daily | OUT | Sep 10, 2026 −5.7% | Enter above $533.32 (+9.9%) | 30% 45/151 | +5.0% / +19.4% | −52.2% / −67.7% |
| Williams AlligatorBill Williams · daily | OUT | Oct 6, 2026 −3.4% | Not on one close | 38% 125/327 | +0.3% / +19.4% | −71.4% / −67.7% |
| Vortex IndicatorEtienne Botes & Douglas Siepman · daily | OUT | Oct 12, 2026 −4.3% | Enter above $559.07 (+15.2%) | 36% 208/570 | +1.4% / +19.4% | −75.3% / −67.7% |
| AroonTushar S. Chande · daily | OUT | Sep 21, 2026 −5.0% | Enter above $529.89 (+9.2%) | 36% 82/229 | +7.4% / +19.4% | −59.5% / −67.7% |
| Parabolic SARJ. Welles Wilder Jr. · daily | OUT | Oct 1, 2026 −4.2% | Enter above $515.74 (+6.3%) | 37% 176/482 | +2.1% / +19.4% | −74.1% / −67.7% |
| ADX TrendJ. Welles Wilder Jr. · daily | OUT | Sep 8, 2026 −8.3% | Enter above $1,309.68 (+169.9%) | 38% 60/156 | +9.7% / +19.4% | −51.1% / −67.7% |
| MACD Zero LineGerald Appel · daily | OUT | Sep 17, 2026 −6.0% | Enter above $578.23 (+19.2%) | 21% 46/215 | +2.4% / +19.4% | −74.3% / −67.7% |
| Zweig 4% ModelMartin Zweig · weekly | OUT | Sep 11, 2026 −5.9% | Enter above $524.92 (+8.2%) | 34% 90/268 | +4.2% / +19.4% | −67.4% / −67.7% |
| MAMA/FAMA CrossJohn F. Ehlers · daily | OUT | Oct 2, 2026 −3.9% | Enter above $879.50 (+81.3%) | 26% 62/241 | +4.1% / +19.4% | −70.8% / −67.7% |
| Schaff Trend CycleDoug Schaff · daily | OUT | Sep 8, 2026 −8.3% | Not on one close | 32% 83/256 | −1.5% / +19.4% | −74.0% / −67.7% |
| Zero Lag EC CrossJohn F. Ehlers & Ric Way · daily | OUT | Oct 1, 2026 −4.2% | Enter above $567.49 (+17.0%) | 23% 46/203 | +1.9% / +19.4% | −74.7% / −67.7% |
| DP Trend ModelCarl Swenlin & Erin Swenlin · daily | OUT | Oct 13, 2026 0.0% | Enter above $523.36 (+7.9%) | 26% 29/111 | +2.3% / +19.4% | −68.6% / −67.7% |
| Elder Triple ScreenAlexander Elder · daily | OUT | Sep 11, 2026 −5.9% | Not on one close | 32% 69/216 | +2.6% / +19.4% | −61.0% / −67.7% |
| Holy GrailLinda Bradford Raschke & Larry Connors · daily | OUT | Jul 10, 2024 −1.3% | Not on one close | 44% 22/50 | +6.0% / +19.4% | −25.0% / −67.7% |
| Breakouts & channels | ||||||
| Four-Week RuleRichard Donchian · daily | OUT | Sep 18, 2026 −4.5% | Enter above $529.89 (+9.2%) | 34% 41/121 | +8.2% / +19.4% | −52.6% / −67.7% |
| Turtle System 1Richard Dennis & William Eckhardt · daily | OUT | Sep 8, 2026 −8.3% | Enter above $533.34 (+9.9%) | 25% 38/150 | +0.2% / +19.4% | −68.1% / −67.7% |
| Turtle System 2Richard Dennis & William Eckhardt · daily | OUT | Sep 18, 2026 −4.5% | Enter above $560.25 (+15.5%) | 29% 27/92 | +5.9% / +19.4% | −42.7% / −67.7% |
| Clenow TrendAndreas F. Clenow · daily | OUT | Sep 10, 2026 −5.7% | Enter above $557.96 (+15.0%) | 26% 28/107 | +1.1% / +19.4% | −63.7% / −67.7% |
| Darvas BoxNicolas Darvas · daily | OUT | Oct 13, 2026 0.0% | Not on one close | 35% 37/107 | +6.9% / +19.4% | −55.9% / −67.7% |
| Keltner ChannelChester W. Keltner & Linda Bradford Raschke · daily | OUT | Sep 8, 2026 −8.3% | Enter above $549.45 (+13.2%) | 30% 47/158 | −0.5% / +19.4% | −63.6% / −67.7% |
| Bollinger BreakoutJohn Bollinger · daily | OUT | Sep 8, 2026 −8.3% | Enter above $535.66 (+10.4%) | 28% 70/248 | −2.5% / +19.4% | −72.5% / −67.7% |
| Chandelier ExitChuck LeBeau · daily | OUT | Sep 10, 2026 −5.7% | Enter above $527.67 (+8.7%) | 31% 58/189 | +4.1% / +19.4% | −65.6% / −67.7% |
| Wilder Volatility SystemJ. Welles Wilder Jr. · daily | OUT | Sep 10, 2026 −5.7% | Enter above $523.23 (+7.8%) | 30% 54/181 | +4.9% / +19.4% | −62.4% / −67.7% |
| P&F Double TopA.W. Cohen & Thomas J. Dorsey · daily | OUT | Sep 21, 2026 −5.0% | Enter above $565.01 (+16.4%) | 40% 55/139 | +8.0% / +19.4% | −61.6% / −67.7% |
| Chande Kroll StopTushar S. Chande & Stanley Kroll · daily | OUT | Sep 8, 2026 −8.3% | Enter above $527.11 (+8.6%) | 22% 83/373 | −1.4% / +19.4% | −81.6% / −67.7% |
| Acceleration BandsPrice Headley · daily | OUT | Aug 26, 2026 −11.3% | Not on one close | 32% 52/164 | +0.7% / +19.4% | −34.3% / −67.7% |
| TTM SqueezeJohn F. Carter · daily | OUT | Aug 28, 2026 −10.4% | Not on one close | 37% 53/144 | +0.4% / +19.4% | −57.3% / −67.7% |
| NR7 BreakoutToby Crabel · daily | OUT | Oct 1, 2026 −4.2% | Enter above $529.72 (+9.2%) | 30% 224/744 | −2.8% / +19.4% | −74.7% / −67.7% |
| Bollinger SqueezeJohn Bollinger · daily | OUT | Sep 8, 2026 −8.3% | Not on one close | 30% 12/40 | +2.9% / +19.4% | −21.6% / −67.7% |
| Momentum | ||||||
| 12-Month MomentumMoskowitz, Ooi & Pedersen · month-end | IN | Jun 30, 2026 −2.3% | Exit below $441.29 (−9.1%) | 28% 9/32 | +7.0% / +19.3% | −77.7% / −67.7% |
| 12-1 MomentumNarasimhan Jegadeesh & Sheridan Titman · month-end | IN | Jun 30, 2026 −2.3% | Not on one close | 38% 15/40 | +10.1% / +19.3% | −75.1% / −67.7% |
| Dual MomentumGary Antonacci · month-end | IN | Aug 31, 2026 −10.9% | Exit below $490.67 (+1.1%) | 35% 13/37 | +7.5% / +19.3% | −55.7% / −67.7% |
| Stocks on the MoveAndreas F. Clenow · daily | OUT | Oct 13, 2026 0.0% | Buy $495.85–$558.00 (+2.2%) | 19% 29/155 | +2.5% / +19.4% | −50.9% / −67.7% |
| 52-Week HighThomas J. George & Chuan-Yang Hwang · month-end | IN | Feb 27, 2026 −2.3% | Exit below $474.26 (−2.3%) | 24% 5/21 | +7.0% / +19.4% | −47.5% / −67.7% |
| Levy Relative StrengthRobert A. Levy · weekly | IN | Aug 14, 2026 −4.1% | Exit below $501.40 (+3.3%) | 25% 33/134 | +1.7% / +19.4% | −77.2% / −67.7% |
| MACD Signal CrossGerald Appel · daily | OUT | Oct 1, 2026 −4.2% | Enter above $527.70 (+8.8%) | 34% 155/458 | +2.3% / +19.4% | −61.7% / −67.7% |
| Elder ImpulseAlexander Elder · daily | OUT | Oct 1, 2026 −4.2% | Enter above $507.01 (+4.5%) | 27% 228/832 | −3.4% / +19.4% | −86.9% / −67.7% |
| Know Sure ThingMartin J. Pring · daily | OUT | Sep 9, 2026 −6.9% | Enter above $582.76 (+20.1%) | 34% 105/308 | −0.3% / +19.4% | −72.7% / −67.7% |
| Coppock CurveEdwin S. C. Coppock · month-end | IN | May 29, 2026 +8.4% | Exit below $208.99 (−56.9%) | 29% 5/17 | +8.9% / +13.4% | −63.7% / −67.7% |
| CCI +100Donald R. Lambert · daily | OUT | Aug 26, 2026 −11.3% | Enter above $544.87 (+12.3%) | 31% 179/580 | +3.0% / +19.4% | −52.0% / −67.7% |
| TRIX Signal CrossJack K. Hutson · daily | OUT | Sep 9, 2026 −6.9% | Enter above $667.91 (+37.7%) | 31% 90/292 | −3.3% / +19.4% | −80.5% / −67.7% |
| TSI Zero LineWilliam Blau · daily | OUT | Sep 18, 2026 −4.5% | Enter above $581.14 (+19.8%) | 22% 46/213 | +2.3% / +19.4% | −75.0% / −67.7% |
| 13612W MomentumWouter J. Keller & Jan Willem Keuning · month-end | IN | May 29, 2026 +8.4% | Exit below $495.23 (+2.1%) | 34% 25/73 | +9.0% / +19.3% | −51.7% / −67.7% |
| Market-State MomentumMichael J. Cooper, Roberto C. Gutierrez Jr. & Allaudeen Hameed · month-end | IN | Jun 30, 2026 −2.3% | Not on one close | 31% 10/32 | +3.2% / +14.3% | −69.1% / −64.0% |
| Frog in the PanZhi Da, Umit G. Gurun & Mitch Warachka · daily | OUT | Apr 30, 2026 +13.5% | Not on one close | 51% 22/43 | +8.7% / +19.3% | −47.7% / −67.7% |
| PMO Signal CrossCarl Swenlin · daily | OUT | Sep 8, 2026 −8.3% | Enter above $558.19 (+15.0%) | 32% 111/352 | −0.6% / +19.4% | −74.2% / −67.7% |
| Mean reversion | ||||||
| RSI 30/70J. Welles Wilder Jr. · daily | OUT | Dec 4, 2025 +6.1% | Not on one close | 50% 16/32 | +5.9% / +19.4% | −61.7% / −67.7% |
| RSI(2) PullbackLarry Connors & Cesar Alvarez · daily | IN | Oct 13, 2026 0.0% | Sell above $501.39 (+3.3%) | 63% 199/315 | +8.2% / +19.4% | −20.0% / −67.7% |
| Double 7sLarry Connors & Cesar Alvarez · daily | IN | Oct 13, 2026 0.0% | Sell above $510.08 (+5.1%) | 65% 265/408 | +13.3% / +19.4% | −50.8% / −67.7% |
| Bollinger ReversionJohn Bollinger · daily | IN | Oct 13, 2026 0.0% | Sell above $511.63 (+5.4%) | 66% 119/179 | +9.1% / +19.4% | −49.4% / −67.7% |
| Stochastic 20/80George C. Lane · daily | IN | Sep 14, 2026 −6.6% | Not on one close | 71% 130/183 | +19.6% / +19.4% | −61.7% / −67.7% |
| Williams %RLarry Williams · daily | IN | Oct 5, 2026 −3.6% | Not on one close | 65% 204/314 | +15.4% / +19.4% | −55.6% / −67.7% |
| DeMark 9-CountTom DeMark · daily | OUT | Jun 25, 2026 +1.0% | Not on one close | 65% 55/84 | +14.7% / +19.4% | −69.1% / −67.7% |
| Mayer MultipleTrace Mayer · daily | IN | Nov 22, 2004 +4,368.0% | Sell above $1,148.84 (+136.8%) | – | +19.4% / +19.4% | −67.7% / −67.7% |
| ConnorsRSI PullbackLarry Connors & Cesar Alvarez & Matt Radtke · daily | OUT | May 13, 2022 +96.7% | Buy below $465.81 (−4.0%) | 42% 8/19 | +0.5% / +19.4% | −32.8% / −67.7% |
| Laguerre RSIJohn F. Ehlers · daily | IN | Oct 13, 2026 0.0% | Not on one close | 48% 168/351 | +8.9% / +19.4% | −65.4% / −67.7% |
| StochRSI 20/80Tushar S. Chande & Stanley Kroll · daily | IN | Oct 9, 2026 −4.9% | Not on one close | 55% 248/448 | +13.1% / +19.4% | −58.8% / −67.7% |
| IBS ReversionAlexander S. Pagonidis · daily | IN | Oct 12, 2026 −4.3% | Sell above $485.22 (0.0%) | 57% 1051/1841 | +10.4% / +19.4% | −36.0% / −67.7% |
| Connors %bLarry Connors & Cesar Alvarez · daily | IN | Sep 14, 2026 −6.6% | Sell above $524.96 (+8.2%) | 65% 68/105 | +4.7% / +19.4% | −69.4% / −67.7% |
| Fisher TransformJohn F. Ehlers · daily | OUT | Oct 13, 2026 0.0% | Enter above $517.60 (+6.7%) | 37% 390/1046 | +3.9% / +19.4% | −56.2% / −67.7% |
| 1-Month ReversalNarasimhan Jegadeesh & Bruce N. Lehmann · month-end | IN | Sep 30, 2026 −7.2% | Sell above $533.36 (+9.9%) | 55% 70/128 | +8.5% / +19.4% | −66.9% / −67.7% |
| Volume & money flow | ||||||
| On-Balance VolumeJoseph E. Granville · daily | OUT | Oct 1, 2026 −4.2% | Not on one close | 24% 200/820 | −0.5% / +19.4% | −90.3% / −67.7% |
| Chaikin Money FlowMarc Chaikin · daily | OUT | Sep 18, 2026 −4.5% | Not on one close | 33% 68/209 | −0.7% / +19.4% | −79.4% / −67.7% |
| Money Flow IndexGene Quong & Avrum Soudack · daily | OUT | Jul 8, 2026 −2.7% | Not on one close | 59% 26/44 | +11.4% / +19.4% | −55.7% / −67.7% |
| Negative Volume IndexNorman Fosback & Paul Dysart · daily | IN | Oct 9, 2026 −4.9% | Exit below $481.82 (−0.7%) | 26% 56/218 | −7.1% / +19.3% | −95.5% / −67.7% |
| Force IndexAlexander Elder · daily | OUT | Sep 30, 2026 −7.2% | Enter above $508.65 (+4.8%) | 23% 178/760 | −1.6% / +19.4% | −89.1% / −67.7% |
| Buff AveragesBuff Dormeier · daily | OUT | Oct 2, 2026 −3.9% | Enter above $569.90 (+17.5%) | 30% 120/402 | −1.2% / +19.4% | −84.3% / −67.7% |
| Chaikin OscillatorMarc Chaikin · daily | OUT | Sep 30, 2026 −7.2% | Not on one close | 36% 207/582 | −0.9% / +19.4% | −78.1% / −67.7% |
| Volume Flow IndicatorMarkos Katsanos · daily | IN | Jun 16, 2026 +7.1% | Not on one close | 22% 26/118 | +3.1% / +19.4% | −69.2% / −67.7% |
| Klinger OscillatorStephen J. Klinger · daily | IN | Oct 9, 2026 −4.9% | Sell $475.58–$494.86 (+2.0%) | 35% 327/937 | +0.1% / +19.4% | −67.7% / −67.7% |
| Candles & chart patterns | ||||||
| Engulfing SwitchSteve Nison & Thomas N. Bulkowski · daily | OUT | May 19, 2026 +11.7% | Enter above $507.55 (+4.6%) | 44% 59/133 | +4.0% / +19.4% | −77.2% / −67.7% |
| HikkakeDaniel L. Chesler · daily | OUT | Apr 21, 2026 +11.1% | Enter above $514.80 (+6.1%) | 29% 37/128 | +1.4% / +19.4% | −81.4% / −67.7% |
| Turtle Soup Plus OneLinda Bradford Raschke & Larry Connors · daily | OUT | May 8, 2026 +12.9% | Enter above $496.15 (+2.3%) | 43% 24/56 | +0.1% / +19.4% | −37.4% / −67.7% |
| Calendar | ||||||
| Halloween IndicatorSven Bouman & Ben Jacobsen & Yale Hirsch & Jeffrey Hirsch · daily | OUT | Apr 30, 2026 +13.5% | Buys Oct 30 | 51% 22/43 | +10.8% / +19.4% | −70.6% / −67.7% |
| Best Six + MACDYale Hirsch & Jeffrey Hirsch · daily | OUT | Apr 27, 2026 +13.9% | Enter above $512.79 (+5.7%) | 53% 23/43 | +7.8% / +19.4% | −72.7% / −67.7% |
| Seasonal TimingSy Harding · daily | OUT | Apr 27, 2026 +13.9% | Window opens Oct 16 | 60% 26/43 | +13.2% / +19.4% | −60.4% / −67.7% |
| Santa Claus RallyYale Hirsch & Jeffrey Hirsch · daily | OUT | Jan 5, 2026 +8.1% | Buys Dec 23 | 36% 16/44 | +1.9% / +19.4% | −14.2% / −67.7% |
| Turn of the MonthJosef Lakonishok & Seymour Smidt & Robert A. Ariel · daily | OUT | Oct 5, 2026 −3.6% | Buys Oct 29 | 48% 254/526 | +3.3% / +19.4% | −55.3% / −67.7% |
| Presidential Sweet SpotYale Hirsch & Jeffrey Hirsch · daily | IN | Sep 30, 2026 −7.2% | Sells Jun 30 | 27% 3/11 | +3.3% / +19.4% | −42.3% / −67.7% |
| Pre-HolidayRobert A. Ariel & Josef Lakonishok & Seymour Smidt · daily | OUT | Sep 4, 2026 −11.2% | Buys Nov 24 | 48% 192/400 | +3.6% / +19.4% | −10.9% / −67.7% |
| January BarometerYale Hirsch & Jeffrey Hirsch · month-end | IN | Dec 30, 2022 +68.0% | Not on one close | 35% 7/20 | +8.9% / +19.4% | −66.2% / −67.7% |
| Weekend EffectKenneth French & Josef Lakonishok & Seymour Smidt · daily | IN | Oct 12, 2026 −4.3% | Sells Oct 16 | 53% 1208/2284 | +21.5% / +19.4% | −52.4% / −67.7% |
| Pre-FOMC DriftDavid Lucca & Emanuel Moench · daily | OUT | Sep 16, 2026 −5.5% | Buys Oct 27 | 49% 172/348 | +3.7% / +19.4% | −24.3% / −67.7% |
| Lunar CycleKathy Yuan, Lu Zheng & Qiaoqiao Zhu · daily | IN | Oct 2, 2026 −3.9% | Sells Oct 16 | 52% 279/541 | +13.0% / +19.4% | −57.8% / −67.7% |
| Benchmark | ||||||
| Buy & HoldJohn C. Bogle · benchmark | IN | Jan 3, 2005 | Always in | – | +19.4% | −67.7% |
Nothing on the checklist stands out.
A crash marks every stock down; debt decides which companies come through. The storm test scores both halves: how hard the stock swings with the market, and how much debt it carries into a downturn. It describes fragility; it does not predict a crash.
Biotechnology · Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain.
| Size and valuation | ||
| Market cap | $123B | What the whole company is worth at today's price: share price × shares outstanding. |
|---|---|---|
| Revenue (last 12 months) | $12.6B | Total sales. The market values it at 9.8× sales. |
| P/E ratio | 28.3× | Buyers pay $28 for each $1 of the last year's profit. |
| Forward P/E | 24.0× | Price against analysts' estimate of next year's profit. Lower than the P/E means profit is expected to grow. |
| Price to book | 6.1× | Price against the company's net assets (its equity) per share. |
| Profit and growth | ||
| Profit margin | 35.0% | Keeps 35¢ of each dollar of sales as profit. |
|---|---|---|
| Revenue growth | +10.2% | The last four quarters' sales against the four before. |
| Earnings growth | +21.7% | Same comparison for profit. |
| Return on equity | 21.8% | Yearly profit as a share of shareholders' money in the business. |
| Free cash flow | $2.6B | Cash left after running and investing in the business. |
| Balance sheet | ||
| Total equity | $18.7B | What it owns minus what it owes. |
|---|---|---|
| Total debt | $2.0B | Loans and bonds it has to pay back, with interest. |
| Cash | $7.9B | Cash and short-term investments on hand. |
| Debt to equity | 0.11× | Comfortable. |
| Interest cover | 350.1× | Interest is easily paid from profit. |
| Wall Street | ||
| Average analyst target | $571.43 | 18% above the close, from 28 analysts (range $350.00 to $667.00). |
|---|---|---|
| Consensus rating | Buy | Analysts' average recommendation. Ratings lean positive: sell ratings are rare. |
P/E, price to sales and book, growth, margin and return on equity from the company's SEC filings for the quarter to 2026-06-30; other company figures from Yahoo Finance, fetched Oct 14, 2026. Analyst targets are opinions, not forecasts Be The Puck checks.
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